Complement in ANCA Vasculitis and IgA nephropathy: Should We Target or Still a Wait Period?
1312 Views
Dr Anna T Valson, Vellore 09 January 2018
IgA nephropathy (IgAN) is the most common type of primary glomerulonephritis worldwide, with patients bearing a broad spectrum of clinical and pathological changes (Zhu L, et al. Kidney Dis. 2015;1(1):27-32).
Complement C3 causes HMCs to convert to the synthetic phenotype and stimulates growth of mesangial cells, suggesting that C3 may play an important role in phenotypic regulation of mesangial cells in renal diseases (Wan JX, et al. J Cell Physiol. 213:495-501).
To comment on this article, create a free account.
Sign Up to instantly get access to 10000+ Articles & 1000+ Cases
eMediNexus provides latest updates on medical news, medical case studies from India. In-depth medical case studies and research designed for doctors and healthcare professionals.